Zytiga Clinical Trials

Abiraterone For Castration-resistant Metastatic Prostate ...
2.1 Abiraterone acetate (Zytiga, Janssen) castration-resistant metastatic prostate cancer that has progressed MRC Clinical Trials Unit Prostate Action C The following individuals were selected from clinical specialist and ... Fetch Document

Medication Policy Manual Policy No: Date Of Origin
Doses have not been demonstrated in clinical trials to be more effective. - Medication Policy Manual, Policy No. dru232 . Provenge NDA 202-379; Zytiga (abiraterone acetate). [cited 12/2/2011]; Available from: ... Retrieve Document

COMBINING ABIRATERONE AND ENZALUTAMIDE FOR HORMONE-NAÏVE ...
COMBINING ABIRATERONE AND ENZALUTAMIDE FOR HORMONE-NAÏVE PROSTATE CANCER >> A POTENTIAL NEW COMPARISON IN STAMPEDE or until PSA, radiological and clinical progression. Figure 4: Potential design from late 2013 Figure 5: Trials. 2012;13(1):168. NEWLY DIAGNOSED M1 PATIENTS 1 ... Get Doc

NEWS RELEASE - Janssenbiotech.com
4 Adrenocortical Insufficiency (AI) - AI has been reported in clinical trials in patients receiving ZYTIGA® in combination with prednisone, after an interruption of daily steroids and/or with concurrent infection or ... Read Full Source

AusPAR Attachment 1: Product Information For Zytiga ...
ZYTIGA tablets contain 250 mg of the active ingredient abiraterone acetate. The tablets also contain the inactive serves as a biomarker in pat ients with prostate cancer. In a phase 3 clinical study of patients who failed prior chemotherapy with taxanes, 29% of patients treated with ... Retrieve Document

Abiraterone: A New Therapy For Metastatic Prostate Cancer ...
On April 28, 2011, the US Food and Drug Administration approved abiraterone acetate (Zytiga) in combination with prednisone for the treatment of metastatic, advanced prostate cancer in men who have received prior chemotherapy. ... View Video

Enzalutamide Versus Abiraterone Acetate For The Treatment Of ...
(AR), and AA (Zytiga), a selective, irreversible inhibitor of cytochrome P17. In addition to discussing the clinical evidence, we also address evolving evidence of mechanisms of PSA based on the original clinical trials examining their efficacy [3-6], ... Visit Document

Abiraterone Acetate - Springer
Of clinical trials for patients with progressive prostate can-cer and castrate levels of testosterone: recommendations of Janssen-Cilag Ltd. Zytiga (abiraterone acetate) 250mg tablets: summary of product characteristics [online]. Available from ... Access Doc

Pan-Canadian Oncology Drug Review Final Clinical Guidance ...
PCODR Final Clinical Guidance Report - Abiraterone acetate (Zytiga) for Metastatic Castration-Resistant Prostate Cancer pERC Meeting: September 19, 2013; Early Conversion: October 22, 2013 ... Fetch Full Source

Nilotinib - Wikipedia, The Free Encyclopedia
Nilotinib (AMN107, trade name Tasigna [2]), in the form of the hydrochloride monohydrate salt, is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia. [3] ... Read Article

HIGHLIGHTS OF PRESCRIBING INFORMATION ...
6 Increased ZYTIGA Exposures with Food [see Warnings and Precautions (5.4)]. 6.1 Clinical TrialExperience Because clinical trials are conducted under widely varying conditions, adverse reaction rates ... Access Document

Clinical Research Charts And Statistics - NC TraCS Institute
Clinical Research Charts and Statistics Zytiga Treatment for Seasonal allergy relief Rheumatoid arthritis Erectile dysfunction Skin infection Osteoarthritis High cholesterol Prostate cancer Years in Clinical Trials Number of Study Volunteers 3,600 13,000 20,000 4,000 3,000 1,794 10,000 ... Retrieve Document

Study Shows Abiraterone Acetate Is Useful Even In Most ...
(Zytiga) led to longer overall disease control, even when a very high Gleason score indicated especially aggressive Flaig was co-investigator of clinical trials that led to FDA approval of abiraterone acetate, and with collaborators continues to explore the best use of ... Fetch Document

Phase 3 trial Confirms Abiraterone Acetate Efficacy For ...
Phase 3 trial confirms abiraterone acetate efficacy for patients with advanced prostate cancer (marketed as Zytiga) offers a significant survival benefit to patients with castration-resistant prostate cancer, which is spreading to other parts clinical trials investigating novel drugs ... Doc Viewer

FRESH FROM THE PIPELINE Abiraterone Acetate
Clinical data The efficacy and safety of abiraterone In April 2011, abiraterone acetate (Zytiga; Centocor Ortho Biotech), in combination with prednisone, was approved by the US the Phase III trials of the second-generation ... Fetch Content

Top 20 Cancer Drugs - Page 2 - Pharma At About.com
Zytiga Manufacturer: Johnson & Johnson. Condition or Diseases treated: Prostate The FDA has allocated "fast track" and break through designation for many of the oncology drugs now in advanced clinical trials so it is expected there will be many new blockbuster cancer drugs in the years ... Read Article

Janssen Oncology Data To Be Presented At 2013 American ...
May 20, 2013 Janssen Oncology Data to be Presented at 2013 American Society of Clinical Oncology (ASCO) Annual Meeting, Including ZYTIGA®, Ibrutinib and Daratumumab Data ... Read Document

Prostate Cancer Market To 2021 - Increasing Disease Prevalence To Be A Key Driver Of Market Growth
LONDON, Jan. 7, 2016 /PRNewswire/ -- Summary Prostate Cancer (PC) is a disease predominately of the elderly with 60% of cases diagnosed in men aged 65 or over. Prostate cancer is slow growing, and asymptomatic at its earliest stages. However, with the use of digital rectal examination, ... Read News

Nutrition And Cancer: Salvestrol Case Studies
3 Nutrition and Cancer: Salvestrol Case Studies with stage 4 melanoma on her foot fol-lowing a biopsy. At time of diagnosis the woman was unable to walk and black ... Document Retrieval

Xgeva Prescribing Information - Amgen
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use Two clinical trials were conducted in patients without cancer and with varying degrees of renal function. In one study, patients ... Return Document

GU Trials Offer Array Of Treatment Options
Through its clinical trials program in genitourinary oncology. An increasing number of clinical trials are based on biomark-ers, immunotherapy and other medical breakthroughs in personalized medicine. These 21st century treatments are no (Zytiga ®) for metastatic ... Fetch Doc

Multidisciplinary Consensus: A Practical Guide For The ...
REVIEW ARTICLE Multidisciplinary consensus: A practical guide for the integration of abiraterone into clinical practice Henry H WOO,1 Stephen BEGBIE,2 Kumar GOGNA,4 Paul N MAINWARING,5 ... Visit Document

Dr. Robert Dreicer Discusses Using Abiraterone Acetate
Robert Dreicer, MD, MS, chairman of the Department of Solid Tumor Oncology at the Taussig Cancer Institute at the Cleveland Clinic, explains that he began using the agent abiraterone acetate (Zytiga) shortly after its approval for metastatic castrate-resistant prostate cancer in April ... View Video

2012-06-15 ZYTIGA SNDA MAA Filing Press Release US Version Final
3 Adrenocortical Insufficiency (AI) - AI has been reported in clinical trials in patients receiving ZYTIGA® in combination with prednisone, after an interruption of daily steroids and/or with concurrent infection or ... Fetch Doc