Yale University Clinical Trials

Organizational Chart: RAS Cancer & Imaging Clinical Trials ...
Thomas Furrie Post-Award Research Administrator Il - Clinical Trials Thomas is an accountant with twenty eight years of research administration experience. ... Access Doc

OPEN ACCESS TO CLINICAL TRIAL DATA? - MedUni Wien
OPEN ACCESS TO CLINICAL TRIAL DATA? Opportunities, challenges and risks • Yale University Open Data Access (YODA) Project on clinical trials on medicinal products for human use ... Doc Viewer

ALS Centers And Clinics - MDA
MDA/ALS Center at Yale University MDA/ALS Clinical Research Center at the University of Wisconsin Madison, WI 53792‐5132. Title: Microsoft Word - ALS Centers and Clinics.docx Author: ksparks Created Date: 5/30/2014 11:20:39 AM ... Access This Document

Modernizing clinical trials - Quintiles
Modernizing clinical trials U.S. Congressional testimony: 21st century cures initiative On July 9, 2014, participants from Harvard University, Yale University, the Mayo Clinic, and Johnson & Johnson – to provide expert testimony in a U.S. Congressional hearing on the topic of modernizing ... Access This Document

Yale University - Connecticut General Assembly
Yale University Stephanie Halene MD Assistant Professor Department of Internal Medicine and Yale Cancer Center, Section of Hematology School of Medicine ... Access Full Source

Conflicting Clinical Trials And The Uncertainty Of Treating ...
Conflicting Clinical Trials and the Uncertainty of Treating Mild Hypertension iology, Yale University School of Medicine, New Haven, Connecticut. Dr. Horwitz is a Henry J. Kaiser Family Foundation Scholar TABLE I Summary of Randomized Clinical Trials of Mild ... Retrieve Full Source

Peter J. McAllister, M.D. Clinical Assistant Professor Of ...
Peter J. McAllister, M.D. Clinical Assistant Professor of Neurology . Yale University School of Medicine, New Haven, Connecticut . Dr. McAllister is a board-certified neurologist and clinical assistant professor of ... Fetch Full Source

Guide To Reviewing Business Agreements And ... - Yale University
Guide to Reviewing Business Agreements and Contracts at Yale and Other Reference Information (Other Than Clinical Trials) 16 Clinical Trials 17 Yale University and the State of Connecticut have entered into contracts ... Retrieve Full Source

Updated Appointment And Promotion Guidelines For The Clinical ...
1 Updated Appointment and Promotion Guidelines for the Clinical Part-time (Voluntary) Faculty of the Department of Internal Medicine, Yale University School of Medicine ... Read Document

The Impact Of Clinical Trials On The Use Of Hormone ...
The Impact of Clinical Trials on the Use of Hormone Replacement Therapy A Population-Based Study Nancy Kim, MD,1,2 Cary Gross, MD, SM2,3,4,6,7 1Section of General Internal Medicine, Yale University School of Medicine, New Haven, CT, USA; 2The Robert Wood Johnson Clinical ... Visit Document

Neuroendovascular Surgery Clinical Trials - YouTube
MD, a neuroendovascular surgeon at Rush, explains the opportunities to participate in clinical trials at Neuroendovascular Surgery Clinical Trials explains the opportunities to participate in clinical trials at the Center for Neuroendovascular Surgery at Rush University ... View Video

How To Get Copies Of Your Medical Records
If you want to get copies of your medical records, then: You must be the patient, or the parent or guardian of the patient for whom you seek records. ... Read Article

Topical Review And Recommendations Core Outcome Measures For ...
Core outcome measures for chronic pain clinical trials: IMMPACT recommendations Robert H. Dworkina,*, Dennis C. Turkb, John T. Farrarc, Jennifer A. Haythornthwaited, fYale University, New Haven, CT, USA gUniversity of Munich, Munich, Germany ... View Document

CURRICULUM VITAE Date Of This Revision: March 2014
CURRICULUM VITAE . Date of this revision: March 2014 . Name: Peter Natale Peduzzi, Ph.D. Ph.D. Yale University (Biometry), 1976 . Career/Academic Appointments: 2010 Fellow, Society for Clinical Trials . ... Fetch Content

Generation Of Pedigree Diagrams For Web ... - Yale University
Generation of Pedigree Diagrams for Web Display Using Scalable Vector Graphics from a Clinical Trials Database Sanjay K. Fernando, MD, MS, Cynthia Brandt, MD, MPH, Prakash Nadkarni, MD ... Doc Viewer

Organizational Chart: RAS Cancer & Imaging Clinical Trials ...
Organizational Chart: RAS Cancer & Imaging -Clinical Trials —08/22/14. Xuandoai Nguyen Post-Award Research Administrator Il - Clinical Trials at Yale University as an Associate Administrator. She returned to Emory ... Read Here

The Meanings And Measurement Of Clinical Significance
Department of Psychology Yale University ABSTRACT The previous articles in this special section make the case for the importance of evaluating the clinical significance of therapeutic change, present key measures and innovative ways in which ... Retrieve Content

Synaffix Appoints World Leading Experts To Scientific Advisory Board And Recruits Chairman To Board Of Directors
Synaffix BV, a biotechnology company exclusively focused on the development of industry-leading antibody-drug conjugate technology, today announced the appointment of a panel of industry experts to its inaugural scientific advisory board . ... Read News

Manuel Elkin Patarroyo - Wikipedia, The Free Encyclopedia
Manuel Elkin Patarroyo Murillo Ataco, Tolima, Colombia: Education: National University of Colombia Rockefeller University : Known for: Malaria license: Medical career: Profession: Doctor: first developed in 1987 in Colombia, was evaluated in clinical trials carried out by the WHO in ... Read Article

Paging Dr. Robot: The Coming AI Health Care Boom
Use of artificial intelligence in health care to grow tenfold in 5 years, say analysts—for everything from cancer diagnosis to diet tips. More than six billion dollars: That's how much health care providers and consumers will be spending every year on artificial intelligence tools by 2021—a tenfold increase from today—according to a new report from research firm Frost & Sullivan. (Specifically ... Read News

CLINICAL TRIALS BIOSKETCH (Complete Curriculum Vitae ...
CLINICAL TRIALS BIOSKETCH (Complete Curriculum Vitae available upon request) Ashraf Thabet, Dr. Thabet earned is MD at Yale University School. After medical school, Clinical Fellow in Abdominal Massachusetts General Hospital, ... Doc Viewer

Yale University Psychotherapy Development Center
Yale University Psychotherapy Development Center Training Series No. 7 Sponsored by NIDA P5O DA 09241 Yale Adherence and Competence Scale (YACSII) ... Read Full Source

Dr. Hyun Bae Talks About Mesoblast Stem Cell Procedure On ...
Dr. Hyun Bae Talks About Mesoblast Stem Cell Procedure on Late He was particularly thrilled with the new results of clinical trials in which he's involved utilizing harvested adult stem from the Yale University School of Medicine. Dr. Bae may be reached through The Spine ... View Video

Yale University Program Of Applied Translational Research ...
Yale University Program of Applied Translational Research: Junior Biostatistician . The Program of Applied Translational Research at Yale (patr.yale.edu) is a from multi-center clinical trials. The Program is looking for an experienced ... Fetch This Document

Xeloda Clinical Trials

Low-dose Capecitabine Adjuvant Chemotherapy In ... - Trials
Low-dose capecitabine adjuvant chemotherapy in elderly stage II/III colorectal cancer ally included, the X-ACT (Xeloda in Adjuvant Colon Cancer Therapy) trial a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85:365–76. 25 ... Retrieve Full Source

Genentech, Inc. XELODA- Capecitabine Tablet, Film Coated
Genentech, Inc.-----HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use XELODA safely and effectively. XELODA has been evaluated in clinical trials in combination with docetaxel (Taxotere®) and as ... Fetch Content

Xeloda Master Word MAR2015 - Genentech
XELODA has been evaluated in clinical trials in combination with docetaxel (Taxotere®) and as monotherapy. In Combination With Docetaxel The dose of XELODA used in the phase 3 clinical trial in combination with docetaxel was based ... Fetch Content

Capecitabine For Locally Advanced And Metastatic Colorectal ...
Capecitabine (Xeloda The clinical evidence from these trials on June 15, 2005, led the U.S. Food and Drug Administration to approve Capecitabine as a single-agent adjuvant treatment for Dukes’ stage C colon cancer patients who have undergone complete resection of ... Get Document

Treatment With Eribulin Mesylate In Metastatic Breast Cancer ...
In this segment, panelists explore the cytotoxic agent eribulin mesylate, which has been the focus of several recent clinical trials. In all, despite a growing focus on targeted therapies, cytotoxics remain an important class of drugs in the treatment of patients with metastatic ... View Video

Top 20 Cancer Drugs - Page 2 - Pharma At About.com
Xeloda Manufacturer: Roche. Condition or Disease treated: Breast, colorectal cancers. The FDA has allocated "fast track" and break through designation for many of the oncology drugs now in advanced clinical trials so it is expected there will be many new blockbuster cancer drugs in the years ... Read Article

XELOX (Capecitabine Plus Oxaliplatin): Active First- Line ...
Capecitabine (Xeloda) in combination with oxali-platin: A phase I, dose-escalation study in pa-tients with advanced or metastatic solid tumors. Ann Oncol 13:558-565, 2002 16. procedure for phase II clinical trials. Biometrics 38:143-151, 1982 22. ... View Full Source

Quality Of Life Under Capecitabine (Xeloda ) In Patients With ...
NIS of Xeloda in Metastatic Breast Cancer Oncol Res Treat 2014;37:748–755 753 Discussion QoL data is mostly collected within clinical trials with strin - ... Retrieve Doc

An Update On Randomized Clinical Trials In Advanced And ...
Randomized Clinical Trials in Advanced and Metastatic Colorectal Carcinoma Shishir K. Maithel, MD, Xeloda), and they suggest that the oral preparation has similar oncologic benefit as theintravenousformandmayactuallybepreferredbysomepatients.12–15 Thisfinding ... Fetch Here

Phase II Study Of Weekly Paclitaxel And Capecitabine In ...
Maceutical company and capecitabine (Xeloda many solid tumors, several clinical trials with triplet chemotherapy (taxane, platinum and 5-FU) demon-strated no superiority to historical doublet chemother-apy regimens in metastatic esophageal cancer,[2] ... Access Full Source

Capecitabine In Stage IV Breast Cancer
Capecitabine in Stage IV Breast Cancer proceedings, and the Physician Data Query Clinical Trials Database were systematically (Xeloda) with paclitaxel in patients with metastatic/advanced breast cancer pretreated with anthracyclines. ... Access Content

Hand-Foot Syndrome - Chemotherapy Side Effects
Hand-foot syndrome is a side effect of many types of cancer drugs. In clinical trials, Xeloda for Metastatic Breast Cancer; Peripheral Neuropathy From Chemotherapy; How to Prevent Acne During Cancer Treatment; ... Read Article

A Patient's Guide To HER2-positive Breast Cancer
Tykerb/Xeloda regimen was a clinical trial of almost 400 women with advanced HER2-positive breast cancer that had progressed breast cancer. Clinical trials involving a total of more than 13,000 patients have found that ... Retrieve Doc

A Critical Review Of The Drug Discovery Process And ...
A Critical Review of the Drug Discovery Process and Properties of Capecitabine (Xeloda) Author(s): Prashad N. The Drug. The path to curing cancer has been a long and testing before being approved for clinical trials. Using primarily mice and monkeys the efficacy of the ... Document Viewer

Brain Metastasis Distribution Of Capecitabine And Its ...
In clinical trials, capecitabine has shown activity against brain metastases of breast cancer. However, the extent of Xeloda (Capecitabine, 150 mg/kg) was administered orally to athymic NuNu mice bearing intracranial MDA-MB-231- ... Read Full Source

Vemurafenib - Wikipedia, The Free Encyclopedia
Clinical trials. In a phase I clinical study, vemurafenib (then known as PLX4032) was able to reduce numbers of cancer cells in over half of a group of 16 patients with advanced melanoma, and the treated group had a median increased survival time of 6 months over the control group. ... Read Article

Ongoing Colorectal Cancer Adjuvant Trials In Japan - Springer
Ongoing Colorectal Cancer Adjuvant Trials in Japan Toshiaki Watanabe Published online: The Japan Clinical Oncology Group (JCOG)-0205 trial is The Xeloda in Adjuvant Colon Cancer Trial (X-ACT) ... Get Doc

Treatments For Pancreatic Cancer
Treatments for Pancreatic Cancer Robert McWilliams, M.D. Medical Oncology, Mayo Clinic Oct 29, 2011 (Xeloda) – Oral; twice daily, hand-foot • Gemcitabine • Always consider participation in clinical trials. 11/2/2011 15 Islet Cell Carcinoma ... Access Document

Xeljanz (tofacitinib) - What You Need To Know - About.com
Clinical trials showed that Xeljanz significantly reduced the signs and symptoms of rheumatoid arthritis and improved physical function Xeljanz (tofacitinib) - What You Need to Know About Health Follow us: We deliver. Get the best of About Health in your inbox. Sign up. ... Read Article

Puma PB272 COMBINATION WITH XELODA 2013
Clinical trials is available at www.clinicaltrials.gov. Puma Biotechnology, Inc. 10880 Wilshire Blvd., Suite 2150 PB272 Combination with Xeloda PB272 Combination with Torisel PB272 Combination with chemotherapy PB272 Combination with Paclitaxel PB272 ... View Doc

Trastuzumab Emtansine - Wikipedia, The Free Encyclopedia
Trastuzumab emtansine (INN; [1] [2] Clinical trials Edit. (Xeloda), with 43% of patients in the trastuzumab emtansine group experiencing severe toxic effects, versus 59% of those who received lapatinib/capecitabine; furthermore, ... Read Article

CANCER - YouTube
Hodgkins Lymphoma Clinical Trials at MD Anderson 3:22. Play next; Play now; MD Anderson Children's Cancer Hospital 3:44. Play next; Cancer: Capecitabine (Xeloda) 5:13. Play next; Play now; Cancer: cMET Pathway 3:37. Play next; Play now; Prostate Cancer & Endothelin 5:01. Play next; Play now; ... View Video

Randomized Phase III Trial Of MFOLFOX7 Or XELOX Plus ...
Randomized Phase III Trial of mFOLFOX7 or XELOX Plus Bevacizumab Versus 5- Brand name(s): Adrucil Xeloda Avastin Eloxatin Abbreviation: clinical trials generally include only elderly patients with few ... Visit Document

Xalkori Clinical Trials

ALK Positive Lung Cancer Definition And Treatment
If you have been told you have ALK positive lung cancer what does that mean? In this case Xalkori binds to the tyrosine kinase receptor on the surface of lung cancer cells and inhibits the New medications are being studied in clinical trials for people who develop ... Read Article

Spigel On Molecular Markers In Clinical Trials SM Pt ... - GRACE
Molecular Markers in Lung Cancer: Who To Test & What to Test For? with Drs. Charles Rudin, Alice Shaw, David Spigel, & Glen Goss Part 5: Promise and Pitfalls of Molecular Markers in Clinical Trials (Dr. Spigel) ... Fetch Doc

U.S. Food And Drug Administration
U.S. Food and Drug Administration. Notice: Archived Document The content in this document is provided on the FDA’s website for reference purposes . only. Clinical trials for rare tumors may only be feasible in the cooperative ... Fetch Document

Cigna Pharmacy Coverage Policy
Cigna Pharmacy Coverage Policy . Subject Crizotinib (Xalkori®) Xalkori is also a P-glycoprotein (P-gp) No randomized, double-blind, comparative clinical trials are published comparing the efficacy of Xalkori with other therapies in NSCLC. ... Access Doc

Special Section: Lung Cancer
Of the Xalkori clinical trials.3 Overall survival was longer in the study participants special section: Clinical Trial Information from the National Cancer Institute: clinical trials, ... Retrieve Here

Early Returns Hint At Strong Successor To Crizotinib New Hope ...
Crizotinib, which Pfizer named Xalkori, was the first new lung cancer drug in six years. Crizotinib has been a success: has also been shown to help these patients in clinical trials. The company is waiting to see if it will be approved by the FDA too. ... Read Full Source

Global Strategic Partners Merck And Pfizer Finalize Agreement ...
News Release 2 treatment settings. To date, globally more than 8,000 patients have been treated with XALKORI, including those who received XALKORI in clinical trials. ... Get Document

XALKORI (crizotinib ) Hard Capsules 200 And 250 Mg For Oral ...
XALKORI (crizotinib ) Hard Capsules 200 and 250 mg for oral use Inclusion of a new warning regarding cardiac failure Dear Healthcare professional, A safety review of crizotinib based on data from clinical trials and reports from clinical practice ... Fetch Here

Enoxaparin Sodium - Wikipedia, The Free Encyclopedia
Enoxaparin sodium is a low molecular weight heparin marketed under the trade names Lovenox, Xaparin and Clexane, among others. [1] It is an anticoagulant used to prevent deep vein thrombosis (DVT) Clinical trials: ... Read Article

Crizotinib: Hunting Another Piece Of The Lung Cancer Genome
Crizotinib: hunting another piece of the lung cancer genome Editorial future science group www.futuremedicine.com 159 cytotoxic drugs, clinical trials with crizotinib ... Access Content

Tandem Tipping Point Xalkori And Zelboraf Prove In 2011 Vs ...
Xalkori and Zelboraf Prove Efficiency of RxDx Strategy By Trista Morrison Editor For years, the drug industry has known its cost of While most drugs languish in clinical trials for upwards of a decade, Zelboraf and Xalkori were able to move quickly, ... Get Doc

Orphan Drug - Wikipedia, The Free Encyclopedia
Small clinical trials and little competition place these "orphan agents" at an advantage when they come up for regulatory review. There is a further reduction to the cost of development because of the tax incentives in the Orphan Drug Act 1983. ... Read Article

Genetic Testing For People With Lung Cancer
Xalkori (crizotonib) was approved by the FDA in 2011 for people whose tumor has an ALK4-EML gene rearrangement; Other medications are being studied in clinical trials, Genetic Testing for People with Lung Cancer About Health Follow us: We deliver. ... Read Article

CRIZOTINIB (XALKORI): IN THE TREATMENT OF ALK-FUSION NON ...
CRIZOTINIB (XALKORI): IN THE TREATMENT OF ALK-FUSION NON SMALL CELL LUNG CANCER clinical trials.[2] Although NSCLCs are associated with cigarette Xalkori capsules are supplied as printed hard-shell capsules containing 250 mg or 200 mg of ... Read More

Method For Identifying Patients For Clinical Trials Based On ...
Method for Identifying Patients for Clinical Trials cancer patients that are ALK -positive for a clinical trial for the drug Xalkori (Crizotinib), where a cohort of ALK -positive patients had an ORR of 61%. Xalkori was granted accelerated approval ... Fetch Document

PRODUCT MONOGRAPH - Pfizer.ca
XALKORI Product Monograph Page 3 of 60 XALKORI Crizotinib Capsules PART I: HEALTH PROFESSIONAL INFORMATION SUMMARY PRODUCT INFORMATION Route of ... Get Content Here

Ventana Receives FDA Approval For The First Fully Automated ...
Media Release Ventana receives FDA approval for the first fully automated IHC companion diagnostic to identify lung cancer patients eligible for XALKORI® (crizotinib) ... View Full Source

New Drugs Approved By The FDA In 2011 - About.com Money
The FDA approved 35 new drugs in 2011, Clinical Trials; FDA Approval; Insurance and Medicare/Medicaid; Manufacturing and Technology; Over-the-Counter Medicine; Xalkori (crizotinib) and companion genetic test for late-stage lung cancer, Pfizer; ... Read Article

Rituximab - Wikipedia, The Free Encyclopedia
Rituximab has been shown to be an effective rheumatoid arthritis treatment in three randomised controlled trials and is now licensed for use in refractory rheumatoid disease. [5] In the United States, Clinical trials: ... Read Article

The Preclinical Profile Of Crizotinib For The Treatment Of ...
The preclinical profile of crizotinib for the treatment of non-small-cell lung cancer and other (Xalkori , Pfizer) was initially devel- Clinical trials for other ALK inhibitors for the treatment ... Access Doc

FRESH FROM THE PIPELINE Crizotinib - Nature
Single-arm clinical trials, known as study A and study B6. Patients with ALK-positive (Tarceva; Genentech/Roche) or gefitinib (Iressa; AstraZeneca). However, with the approval of crizotinib (Xalkori; Pfizer) by the US Food and Drug Administration, there is now an option for the estimated ... Content Retrieval

Management Of NSCLC: Focus On Crizotinib
Clinical trials with crizotinib in ALK-positive NSCLC 4. Crizotinib safety profile 5. Mechanisms of acquired resistance to crizotinib 6. Crizotinib (PF 02341066, Xalkori; Pfizer Inc., New York, NY) (Box 1), an oral selective TKI of both ALK and mesen- ... Read Content

OxOnc! Announces! Agreement! With! Pfizer! To! Develop ...
Execute(clinical(trials.(((OxOnc(is(funded(by(Orbimed(Advisors,(a(leading(venture Crizotinib!(Xalkori®)!has!receivedconditional!marketingauthorization!in!the!EU!for!the!treatment!of!adults!withpreviously treated!ALKDpositive!advanced!NSCLC.! 2! ... View Document

Alliance For Clinical Trials In Oncology NEWS
Alliance for Clinical Trials in Oncology Spring 2015 Volume 5, No. 2 info@allianceNCTN.org NEWS ANNUAL MEETING 2015 Spring Group Meeting Convenes May 13-16 (Xalkori) or erlotinib (Tarceva) will prevent recurrence and improve survival. ... Return Doc

The Role Of Non-Randomized Trials For The
Non-Randomized Trials for the Evaluation of Oncology Drugs: XALKORI ® Approval. The Conditional power calculations for clinical trials with historical controls. Stat in Med 25:2922-31, 2006. Number of patients needed on test treatment ... Fetch Content

Freda Lewis-Hall, M.D., DFAPA
XALKORI®, which is indicated for the treatment of patients with metastatic NSCLC whose tumors are phase 3 clinical trials, where XALKORI was compared directly to chemotherapy in either patients with previously treated12 or patients with previously untreated3 ALK-positive metastatic NSCLC. ... Visit Document

Dr. Maurie Markman On The PROFILE 1007 Crizotinib Trial
Dr. Maurie Markman on the PROFILE 1007 Crizotinib Trial Targeted Oncology. Subscribe one arm to the other also saw PFS benefit and Markman believes that PFS should be the standard enpoint in all oncology trials. Category Phase 1 Clinical Trial for ALK-Driven ... View Video