Rheumatoid Arthritis Clinical Trials

Clinical Management Of Septic Arthritis
For septic arthritis asseeninpatients with rheumatoid arthritis There are no randomized controlled trials that have Table 1 Pathogen-specific clinical scenarios for septic arthritis Clinical History Joint Involvement Pathogen Cellulitis, skin infection [86] ... Return Doc

Guidance For Industry - Food And Drug Administration
Guidance for Industry . Rheumatoid Arthritis: Developing Drug Products for Treatment . Additional copies are available from: Office of Communications, Division of Drug Information ... Visit Document

Belimumab - Wikipedia, The Free Encyclopedia
Phase II trials of belimumab for rheumatoid arthritis were unsuccessful. GlaxoSmithKline acquired HGS, took belimumab through Phase III clinical trials, and markets belimumab. [6 Uses Systemic lupus erythematosus. While belimumab appears safe in systemic lupus erythematosus, the ... Read Article

Rheumatology - Wikipedia, The Free Encyclopedia
Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis: Significant tests: Scientific research on biologics and clinical trials on monoclonal antibody therapies have added a new dimension to the medical treatment of arthritic disorders. References Edit External ... Read Article

Quantitative Measures For Assessing rheumatoid arthritis In ...
4 Quantitative measures for assessing rheumatoid arthritis in clinical trials and clinical care Theodore Pincus* MD Professor of Medicine Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, ... Retrieve Document

Polymyalgia Rheumatica - What You Need To Know
Polymyalgia rheumatica is typically associated with aching and stiffness of the shoulders and hips. It is sometimes confused with rheumatoid arthritis. clinical signs and symptoms, ... Read Article

AbbVie Kicks Off Phase 3 Program For ABT-494 In Rheumatoid Arthritis
AbbVie ( ABBV +0.1% ) commences Phase 3 development of ABT-494, an investigational, once-daily JAK1 inhibitor, for the treatment of rheumatoid arthritis (RA). The program, comprised of five clinical trials, will include patients who do not respond adequately to conventional or biologic disease-modifying antirheumatic drugs (DMARDs) and those who have not been treated with methotrexate (MTX). ... Read News

Guidance For Industry - Food And Drug Administration
Guidance for Industry Clinical Development Programs for Drugs, Devices, and Biological Products for the Treatment of Rheumatoid Arthritis (RA) Additional copies of this Guidance are available from: ... View Doc

From Desk To Bed: Computational Simulations Provide ...
RESEARCH ARTICLE Open Access From desk to bed: Computational simulations provide indication for rheumatoid arthritis clinical trials Jennifer E Dent1,2* and Christine Nardini1* ... View Document

Our Current clinical trials - Arthritis Research UK
Our current clinical trials Arthritis Research UK has an active and ever-growing portfolio of clinical trials into a number of different types of arthritis and musculoskeletal conditions. ... Content Retrieval

Has The rheumatoid arthritis (RA) Core Outcome Set ... - Trials
Has the rheumatoid arthritis (RA) core outcome set influenced the selection of study outcome measures? outcomes for rheumatoid arthritis clinical trials, origi-nating from the OMERACT (Outcome Measures in Rheumatology) Initiative. Methods ... Visit Document

Rheumatoid Arthritis: MRI As An Efficacy Endpoint In Clinical ...
FDA, in which MRI is judged as an unsubstantiated representation of clinical change (6). However, more than a decade has passed since this guidance was issued, and new ... Get Document

Treat-to-target In rheumatoid arthritis: clinical And ...
Treat-to-target in rheumatoid arthritis: clinical and pharmacoeconomic considerations. Introduction G. Turchetti, J.S. Smolen, A. Kavanaugh, J. Braun, Review of clinical trials which provide the intellectual foun-dation for treat-to-target in rheumatoid arthritis, based on a ... Retrieve Full Source

Quantitative Measures And Indices To Assess rheumatoid ...
Quantitative measures and indices to assess rheumatoid arthritis in clinical trials and clinical care Theodore Pincus, MDa,*, Tuulikki Sokka, MD, PhDa,b ... Fetch Full Source

Rheumatoid Arthritis (RA)
Rheumatoid Arthritis (RA) A Study to Evaluate the Safety and Efficacy of 2 Doses of CP-690,550 in People with Active Rheumatoid Arthritis While ... View Full Source

Clinical Trials - Rheumatoid Arthritis - NYU School Of Medicine
Rheumatoid Arthritis (RA) B cell T cell Antigen-presenting cells B cell or macrophage Synoviocytes Pannus Articular cartilage Chondrocytes Macrophage HLA -DR ... Fetch Full Source

TNF Inhibitor - Wikipedia, The Free Encyclopedia
However, subsequent clinical trials in patients with sepsis showed no significant benefit. Clinical application of anti-TNF drugs in rheumatoid arthritis was demonstrated by Marc Feldmann and Ravinder N. Maini, who won the 2003 Lasker Award for their work. [16] ... Read Article

Psoriatic arthritis Assessment Tools In clinical trials - GRAPPA
Psoriatic arthritis assessment tools in clinical trials group was founded as Outcome Measures in Rheumatoid Arthritis Clinical Trials, hence the acronym, but has since expanded its mission across the spectrum of rheumatology intervention studies.) ... Access Document

MSM was touted as a cure for arthritis. It's not a cure but how does MSM work to relieve rheumatoid arthritis; gout; clinical trials that have indicated that MSM is effective for osteoarthritis. One of the studies was published by the journal, Osteoarthritis and ... Read Article

Feasibility Impact On Operational Delivery Strategy In Asia ...
Video abstract of review paper "Case series of feasibility considerations that impact operational delivery strategy in the highly competitive rheumatoid arthritis space in Asia" published in the Open Access Journal of Clinical Trials by Karen Wai, Lisa Marie Saldanha, Elvira Zenaida ... View Video

RAPID3, An Index To Patients With Rheumatoid - The Clinics
RAPID3, an Index to Assess and Monitor Patients with Rheumatoid Arthritis, Without Formal Joint Counts: Similar Results to DAS28 and CDAI in Clinical Trials and ... Fetch This Document

Clinical trials In rheumatoid arthritis: A Status Report From ...
Rheumatol Int (2012) 32:1831–1835 DOI 10.1007/s00296-011-2027-3 123 SHORT COMMUNICATION Clinical trials in rheumatoid arthritis: a status report ... Read Here

PDF - Arthritis Research & Therapy
Introduction Among patients with rheumatoid arthritis (RA), disease progression over time is difficult to predict. Demographic, clinical, laboratory, and imaging parameters, both alone ... Read Content

DOI 10.1002/art. Arthritis & Rheumatism
Against Rheumatism definitions of remission in rheumatoid arthritis clinical trials* Boolean-based definition: At any time point, patient must satisfy all of the following: ... Fetch This Document

Clinical Trials: Biologics - Phrma.org
Clinical Trials: Biologics The 794 clinical trials listed here include 419 that have not yet started recruiting patients or Musculoskeletal Disorders/Arthritis – 33 Active clinical Trials Rheumatoid Arthritis is listed under Autoimmune Disorders ... Access This Document

PDF - Arthritis Research & Therapy
RESEARCH ARTICLE Open Access Changes in serum creatinine in patients with active rheumatoid arthritis treated with tofacitinib: results from clinical trials ... Read More

Outcome Measures In rheumatoid arthritis Randomised trials ...
Associations for Rheumatology core set of outcomes for rheumatoid arthritis clinical trials, originating from the OMERACT (Outcome Measures in Rheumatology) Initiative. This study assesses the use of this core outcome set by randomised trials in rheumatology. ... Access Full Source

Rheumatoid Arthritis Drugs In The Pipeline - arthritis.about.com
What's in the drug pipeline for rheumatoid arthritis? There are drugs currently in development for rheumatoid arthritis. It is the drugs that reach Phase 3 clinical trials which are most worthy of our attention. ... Read Article